Alpha-1-antitrypsin globules in the liver and PiM phenotype.
نویسنده
چکیده
The finding is recorded of typical a1-antitrypsin globules, confirmed by immunofluorescence and immunoperoxidase methods, in the hepatocytes of a patient shown to have a normal serum antitrypsin level and normal phenotype (TiM) for a1-antitrypsin. The identification of such globules can no longer be regarded as conclusive evidence of an abnormal a1-antitrypsin phenotype.
منابع مشابه
Determination of Alpha 1-Antitrypsin Phenotypes and Genotypes in Iranian Patients
Alpha 1-antitrypsin (AAT) or alpha 1-protease inhibitor (PI) is the principal inhibitor of proteolytic enzyme in serum. Its phenotypic variability has been reported to be associated with liver, lung diseases and rheumatoid arthritis in humans. There is much documentation about high risk phenotypes of PI in some regions of the world, however, there are no reliable reports on these phenotypes and...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 30 5 شماره
صفحات -
تاریخ انتشار 1977